2018年2月24日星期六

Is uremia "incurable"

Because uremia is a general condition that causes disorganization of the body system during uremia, this leads to refractory uremia.

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Uremia why refractory? We say refractory, then it is not treated uremia bad? Of course, experts do not answer, although uremia is refractory, but not can not rule that uremia is incurable disease this lack of basis, but also based on the lack of understanding of the disease. The occurrence of uremia, in essence, is the health of the kidneys to damage, and then to damage until the final loss of function. Intrinsic cells in the kidney gradually fibrosis, sclerosis. In the process of renal fibrosis, the innate cells of the kidney are damaged, the phenotype of the cells is transformed, and the cells harden, accompanied by a loss of function. The more serious loss, the fewer healthy nephrons, the body's various laboratory indicators such as serum creatinine, blood urea nitrogen quickly beyond the scope of the more out of range, more and more weak renal function, and finally to the failure, end-stage renal failure Is uremia period. In other words, if you want to treat kidney disease, uremia, these kidney disease, we must do to block the development and renal disease link. Once these links are blocked, on the one hand, it blocks the possibility of renal failure to kidney failure and uremia. On the other hand, on the basis of controlling the development of severe diseases, it further clears various inflammatory mediators in the kidney to promote Reversal of damaged kidney inherent cells, the repair of residual renal cells, make the complete rehabilitation of kidney disease has become a reality.

Although uremia is refractory, but not can not cure. Currently kidney replacement therapy  include: hemodialysis, peritoneal dialysis and kidney transplantation.

Hemodialysis is the introduction of the patient's blood and dialysis simultaneously dialysis membrane on both sides of the membrane through the semi-permeable membrane to clear the metabolic waste, to correct electrolyte and acid-base imbalance, and remove excess body water. Hemodialysis can partially replace renal function, which is one of the widely used uremic treatment methods.


Peritoneal Dialysis The human body's own peritoneum is used as a dialysis membrane for blood purification. The dialysate is introduced into the abdominal cavity of the patient, the toxins in the blood and excess water are passed through the peritoneum into the dialysate in the abdominal cavity and excreted. Regular or continuous replacement of the dialysate in the abdominal cavity, to purify the blood purpose.

Renal transplantation is the implantation of other people's kidneys into the body of patients with uremia by surgery to function. Implantation of the kidney can completely replace the function of the kidney, which is the most effective and long-term cost-effective treatment for uremia. It is also recognized as the best uremic treatment.

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