2018年4月13日星期五

What is the difference with proteinuria

What is microalbuminuria? What is the difference with proteinuria? Nephropathy patients need to understand, the relationship between urinary microalbumin, urinary protein, and the relationship between urinary protein and renal physicians. After reading, it is known that urine is a very common examination item for patients with kidney disease, but regarding protein, Urine microalbumin, urinary protein, etc., many patients with kidney disease expressed confusion: What are the differences between these two tests?

Clinical significance of urinary protein
It is well-known that there is a plus sign for urine protein, which usually means that the kidneys are damaged. Therefore, urinary protein is one of the important criteria for judging kidney disease.
But there is a problem here: physiological urine protein.
Although the kidney is not damaged, but due to various reasons such as body position, diet, exercise, etc., it will also cause urinary protein plus sign.
Therefore, when there is a plus sign for urinary protein, the doctor will usually ask the patient to do 24-hour urinary protein quantification for further confirmation.
However, it is inconvenient to make 24 urine protein quantification. It involves the collection and preservation of urine and may require hospitalization. Therefore, a test item named "urine protein creatinine ratio" is also called, which is abbreviated as ACR.
ACR is generally used to detect random urine, and the value has a very significant positive correlation with 24-hour urinary protein quantification, so it can well replace 24-hour urinary protein quantitation.
Clinical Significance of Microalbuminuria
The urinary protein test is so rough that although ACR or 24-hour urinary protein quantification can be used as a supplement, there are still some cases that are easily overlooked.
For example, early kidney damage caused by hypertension and diabetes.
This kind of protein leakage caused by elevated glomerular pressure, urinary protein added in the early days, but this time has caused kidney damage, and more importantly, this stage is the best time for treatment.
In order not to miss this optimal treatment opportunity, we have found urinary microalbumin as a solution.
As the name suggests, urinary microalbumin is used to detect urinary proteins below 0.15g/24h.
This is one of the important criteria for early diagnosis of secondary nephropathy such as diabetic nephropathy and hypertensive nephropathy.
The order of urine test in patients with kidney disease
In general, for a newly diagnosed kidney patient, the order of urine tests is probably this:
1, no history of diabetes, hypertension
First check the urine routine. If everything is OK, it's fine. If urinary protein is added, 24-hour urinary protein quantification is required.
If the 24-hour urinary protein quantification is not convenient, ACR can be done.
At this point, you can basically confirm whether or not you have kidney disease.
2, there is a history of diabetes, hypertension
First check the urine routine, if everything is normal, you also need to check urinary albumin for further judgment.
The following steps are consistent with the former case.
Here, everyone should understand the relationship between urinary microalbumin and urinary protein, and also understand why these tests are performed.

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