Diabetes is a metabolic disease characterized by hyperglycemia. Due to insulin secretion, insulin action or both defects, causing sugar, protein, fat, water, electrolyte metabolic disorders. Many complications of diabetes, including diabetic nephropathy is the most common, but also one of the major causes of death in patients with diabetes. For the simplest diagnosis of nephropathy is to check the urine, of which the most important test for urinary protein, urinary protein positive if the kidney may be sick, early symptoms and signs of diabetic nephropathy, urine protein routine tests are mostly negative. This brings difficulties to early diagnosis.
In 102 cases of health examination results, MA were less than 19mg / L, did not detect urine MA positive, the positive rate of 0.
Of the 159 patients with type 2 diabetes mellitus, 13 out of 51 diabetic patients with a history of 5 years had positive urine MA with a positive rate of 53.1%. Of the 33 diabetic patients with a history of more than 10 years and 15 years, 20 cases of urine MA positive detection, the positive rate was 60.61%; history of more than 15 years in less than 20 years 36 cases of diabetic patients, 29 cases detected urine MA positive, the positive rate was 80.56%; history of more than 20 years Of the seven patients with diabetes mellitus, six cases of urine MA positive detection, the positive rate was 85.7%. Urinary MA and diabetes history are closely related.
Urine microalbumin is an important indicator of early kidney damage, so for patients with diabetic nephropathy, early detection of urinary microalbumin is very necessary, because patients with microalbuminuria have a way to treat, can make the condition improved, when patients develop to clinical Albuminuria, the treatment is more difficult. If further urinary protein renal dysfunction, it is more difficult to treat, then progress to uremia is unlikely to reverse the condition.
Development of uremia, only dialysis or kidney transplantation treatment, the treatment of this period, not only the patient is very painful, but also tens of thousands of costs, far more than check urine protein, urine protein costs. Therefore, for patients with diabetes, urine microalbumin detection is an early diagnosis and treatment of diabetes patients the main part. The group of 159 patients with type 2 diabetes mellitus patients with urine MA total positive rate was 49.1%, 102 cases of control group urine MA positive rate was 0, the difference between the two groups was statistically significant (P <0.01) . It can be considered urine MA detection of diabetic patients with renal damage is important. Urine MA is closely related to the history of diabetes. The longer the history of diabetes mellitus, the higher the positive rate of urinary MA. With the prolongation of history, the positive rate of urinary MA increased year by year from 25.5% to 85.7% Not obvious. In short, diabetes mellitus urine MA and the history was positively correlated, the longer the history, the higher the positive degree of MA, the more severe renal damage.
In recent years, urine MA testing has been the doctor, the patient's attention, testing methods are constantly updated, with biochemical analyzer urine microalbumin, the operation more simple, convenient, fast, high sensitivity and accurate and reliable results. Detection of urine MA detection of diabetic nephropathy has very important clinical value, so in the long run, accurately detect the level of urinary MA in diabetic patients to seize the stage of microalbuminuria can be reversed, the diagnosis and treatment of diabetic nephropathy is very important.
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