What can't be ignored in the treatment of lupus nephritis

Nephrologists: Never to be ignored in the treatment of lupus nephritis
problem:
1. What are the difficulties in the treatment of lupus nephritis?
2. What can't be ignored in the treatment of lupus nephritis?

Correct understanding of lupus nephritis
Lupus nephritis is one of the organ damages caused by systemic lupus erythematosus. Although the cause of lupus erythematosus is not yet clear, it will produce a large number of autoantibodies, form immune complexes, and cause damage to the kidneys.
It should be noted that lupus erythematosus causes damage to multiple systems such as the skin, nervous system, cardiovascular system, respiratory system, and digestive system. Therefore, it is necessary to take into consideration the overall situation during the treatment of lupus nephritis.
There is a saying that lupus erythematosus damage to multiple systems is very similar to that of uremia. Therefore, lupus nephritis is also called "uremia that is not uremia."

Types of lupus nephritis
Lupus nephritis does not have a uniform classification. The WHO classification is currently used. Lupus kidney is divided into six types:
1 mild lesion type
There was no injury or only minor injury to the kidneys. Kidney puncture showed a small deposition of immune complexes and almost no renal symptoms.
Treatment: This type is mainly for the treatment of lupus erythematosus, if properly controlled, can avoid the development of kidney damage.
2 mesangial proliferation
In the glomerular mesangial area, there is damage, mainly mesangial proliferation caused by the deposition of immune complexes. The clinical manifestations are mild hematuria and proteinuria.
Treatment: Urinary protein will further destroy the renal filtration barrier and need to be eliminated in time.
3 Focal segment proliferation
There is segmental glomerular lesions. In addition to hematuria and proteinuria, hypertension may occur in clinical manifestations. A small percentage of patients experience mild renal impairment (decrease in endogenous creatinine clearance). Some patients may show Nephrotic syndrome.
Treatment: The elimination of urine protein has become the focus of treatment, especially in patients with nephrotic syndrome. In addition, it is more important to clear immune complexes.
4 diffuse proliferation type
More than half of patients with lupus nephritis belong to this type. Almost all glomeruli have been damaged, and there is also severe tubulointerstitial damage. Proliferation in capillaries, thickening of capillary walls, formation of crescents, etc. occur, and glomerulosclerosis occurs in some patients. The clinical manifestations are severe hematuria, proteinuria, hypertension, nephrotic syndrome, etc., and most patients have renal insufficiency.
Treatment: In addition to the elimination of symptomatic treatment such as urinary protein, hematuria, and hypertension, plasma exchange is usually used to prevent further deterioration of the condition.
5 membranous nephropathy
Diaphragmatic spasm and diffuse thickening of the basement membrane is the main pathological changes of this type of clinical manifestations of nephrotic syndrome.
Treatment: Similar to membranous nephropathy, in the elimination of urine protein, but also use traditional Chinese medicine to clean immune complexes.
6 glomerular sclerosis
Deposition of immune complexes causes renal cell ischemia and hypoxia, causing glomerular massive sclerosis, and a dramatic decline in renal function. The clinical manifestations are mainly renal failure-related symptoms.
Treatment: Maintaining residual renal function and improving renal microcirculation can improve the quality of life of patients.
Please note: The above types can exist at the same time, and some types can be converted to each other.

Treatment of lupus nephritis can not be ignored
1 Systemic lupus erythematosus (SLE) is a multi-system impaired systemic disease. It is important not to focus on kidney damage during treatment.
2 Lupus nephritis is a more serious form of systemic lupus erythematosus damage, so treatment can not be easily interrupted.
3 Elimination of urinary protein is only a means to avoid further damage to the renal filtration barrier. The focus of the treatment of lupus erythematosus nephritis lies in the clearance of immune complexes.

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How to overcome stubborn edema

“Due to Lupus Nephritis, I get many symptoms, including serious edema on the whole body, poor sleep, swollen abdomen, nausea and vomiting. Before coming to the hospital, I never thought how should I do, the only thing is to wait for death. Thanks very much for the great Chinese medicine, thanks for the doctors and nurses here. If without them, I would not gain rebirth.” LIMA told us with a smile.

Disease History

LIMA is 31 years old. Seven years ago she was diagnosed with Stage 4 Lupus Nephritis, blood pressure was 130/80mmHg, proteinuria 4+, occult blood 2+, and then joint pain, fever, and dermatitis appeared. Five months ago, she found her blood pressure reached to 140/80mmHg, proteinuria 2+, and occult blood 1+. What is worse, her whole body started to have serious edema, which made her could not walk normally, just lie on the bed. So it is no stranger that she came to our hospital in a wheelchair.

Check-up in Beijing Tongshantang Hospital of TCM

After she arrived at our hospital, our doctor did a systematic check-up for her, which showed her blood pressure 180/120mmHg, proteinuria 3+, occult blood 1+, total protein 65.1 g/L, albumin 33.0g/L, triglyceride 0.95mmol/L, total cholesterol 3.81mmol/L, and weight 59.8kg.

Diagnosis: Stage 5 Lupus Nephritis, Renal Anemia, and Renal Hypertension, etc.

Treatment Schedule

To ensure she could get effective therapy, we invited experts to make treatment schedule according to her years of illness condition, including plasma exchange, diuretic treatment, Chinese medicine treatment, etc.

Chinese medicine treatments have Micro-Chinese Medicine Osmotherapy (2/day) to improve the microcirculation of kidneys, Chinese herbal foot bath (2/day) to dredge collaterals and promote blood circulation, and steaming therapy (1/day) to relieve her symptoms, such as fatigue, weakness, and poor sleep.

Curative Effects

Through 15 days of treatments, her edema started to disappear. Nausea and vomiting had been improved greatly. Under the diet guidance of nurse, her body became better and better. Each day she would have a walk in the hall with nurse. About 20 days, the examination showed her blood pressure was controlled in 130/90mmHg, proteinuria reduced to 1+. After 25 days of treatment, her condition kept stable and in order to consolidate the condition, she were willing to take medicines at home. Now, LIMA’s condition has been controlled well, and she starts a new life without edema.

Email : kdtinchina@yahoo.com 

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Beijing Tongshantang Hospital of Traditional Chinese Medicine

Beijing Tongshantang Hospital of Traditional Chinese Medicine co., LTD registered in November 2016, has the registered capital of 50 million yuan. It is the hospital of traditional Chinese medicine which inherits the quintessence of Chinese culture and treats patients with high-end demand. It has been approved as the second class Chinese medicine hospital by Beijing Changping District Health and Family Planning Commission. The construction area of Building 1 and Building 3 is more than 60 thousands square meters. Moreover, it has 300 beds and the number of staff is 363, including doctors, nurses and medical technicians.

The main departments include : internal medicine department (major in cardiovascular medicine, major in nephrology), surgical department, obstetricians and gynaecologists department (major in gynecology), oncology department, laboratory medicine department, radiology department, integrated department Chinese and Western medicine, Chinese medicine department (internal, surgery, gynecology, pediatric, acupuncture, massage, rehabilitation department).

Part Two: Hospital’s Four Characteristics

1. First-class team of experts.
① International Expert Consultation Center of 100 professors, is headed by Daning Zhang, Yaoxian Wang, Xiaohong Cheng, Hongtao Yang and Hang Li.
② International Expert Consultation Centre of Cerebrovascular Disease, Xingquan Zhao of Beijing Tiantan hospital.
③ International Expert Consultation Centre of Cardiovascular Disease, including 30 professors headed by Mingying Wu of Beijing Tongren Hospital.
④ International Expert Consultation Centre of Cancer, including 30 professors headed by Lijuan Niu of Chinese Academy of Medical Sciences Cancer Hospital.
2. Special treatment.
The overall idea of Beijing Tongshantang Hospital of Traditional Chinese Medicine is to serve special patient group with high end equipment and top specialists.
The general idea is a aggregation in which it is started with international patient, and then driven by domestic and foreign high-end group.
3. First-rate equipment and hardware.

All the equipment is equipped within a year. It includes ECT, CT, CR and MR. Configuration method: self mining and cooperation.
4. Excellent service.
   Standard Listed Hospital.
   Superior doctor,nurse and translator team.
   Intellectualized system is put into use in pre-hospital, hospital, after hospital discharge.
   High charge and superior services.
   55566 development module.

Part Three: Introduction of Main Departments

1. Traditional Chinese Medicine Department
There are 12 chief physician, 18 associate chief physicians, 23 attending doctors, 12 nurse practitioner and 20 nurses in the department.
The Department makes use of not only traditional Chinese medicine treatment, but also Chinese Medicine Colon Dialysis Machine, Chinese Medicine Steam Machine, Moxibustion Bed and other advanced equipment.
Traditional Chinese Medicine Department adopts TCM syndrome differentiation to carry out the characteristic treatments according to the patient’s personally illness condition. The characteristic treatments are composed of 11 therapies: Oral Chinese Herbal Treatment, Chinese Herbal Hot Compress Therapy, Chinese Herbal Feet Bath, Chinese Herbal Inunction Therapy, Chinese Herbal Medicated Bath, Acupuncture Therapy, Chinese Herbal Moxibustion Therapy, Chinese Herbal Fumigation and Steaming Therapy, Enema Therapy, Chinese Herbal Matching Acupoint Therapy etc. They can take good effects on treating all kinds of chronic diseases, and can prevent these diseases.

2. Laboratory Department
Currently Clinical Laboratory has Roche C311 automatic biochemical analyzer,Sysmex CA-1300 blood coagulation analyzer，Sysmex XN-1000 blood cell analyzer, Sysmex UF-500 Full automatic urine type composition analyzer and other equipment. Nearly 100 test items can be carried out.
3. Blood Purification Center
Blood Purification Center covers an area of 800 square meters and includes treatment area, waiting area, VIP treatment area, Independent water treatment equipment area and so on. It has complete matching facilities. Clean area, contaminated area, isolated dialysis treatment area are completely separated and rational layout. There is no cross infection so as to ensure medical safety.
Currently the open dialysis beds are 70. Dialysis equipment and supplies are all advanced products in the world, including 30 of Germany Braun hemodialysis machines, 18 of Germany Braun Hemodialysis filtration machine, and 15 of Beijing Daybreak DX-10 hemodialysis machines. The standard on-line hemodiafiltration is adopted, which can effectively eliminate micro-molecule, middle-molecule, macro-molecule toxins, greatly improving the living quality and prognosis of patients.
Staff in Blood Purification center have rich experience in dialysis. Amongst there are 6 of chief physicians, 11 of associate chief physician and 23 nurses. All of them have received provincial hospital dialysis professional learning, and regularly invite famous experts to the hospital for operational guidance and health guidance to the patients.
Besides, various blood purification techniques are carried out in the Blood Purification Center, such as Hemodialysis, Hemodiafiltration, Hemoperfusion, CRRT, Plasma Exchange, Immunoadsorption, etc.
4. Imaging Department

It has been initially equipped with 1 DR——New Oriental 1000D, 1 Color Doppler——Philips Q7, which is no film, networking, and informatization, shorting the time of report. In the following, we will configure CT, MRI and other large equipment as well as a powerful image storage and transmission system so as to reduce the rate of missed diagnosis, providing a better service for patients.
5. Pharmacy
Our hospital has a pharmacy for Chinese medicine and western medicine, which has complete medicine, well-equipped facilities, and strong pharmacists.
The usable area of pharmacy is over 700 square meters, and there are 6 chief pharmacists and 11 pharmacists for Chinese medicine and western medicine.
The pharmacy is divided into acceptance area, storage room for Chinese medicine and western medicine, pharmacy for Chinese medicine and western medicine, prescription department and decoction room so as to meet clinical need.
6. Inpatient ward
Each ward has a 24-hour hot water, bathroom, wall-mounted LCD TV, outside calls, sofas, refrigerators, special multi-function shaking beds for hospital, and medical professional kitchen. Ward is divided into luxury suites, VIP suites, suites and general ward,with elegant, clean, comfortable and quiet living environment. In addition, there are also leisure centers and Muslim restaurants that cater to the needs of patients and families of different religious beliefs.

Part Four: Overall View of Medical Experts Team

1. High-quality medical team
At present, the hospital has a total of 363 medical and nursing staff, of whom 103 were doctors, 127 nurses and 133 medical technicians, except for administrative staff and logistic support staff.
2. The international high standard of medical service
The international department adopts Dedicated Staff and Full Service mode. The national experts, provincial experts and hospital experts "three linkage" work together for each patient' s diagnosis, and we ensure foreign patients' communication during the whole treatment process by full-time English nurses and translators.

Part Five: Hospital's International Development Goals

Now we have made contact with dozens of Ambassadors to China, including Oman, Saudi Arabia, Morocco, Bahrain, Bangladesh, India, UAE, Palestine, Iraq, Libya, Zambia, Nigeria and Kenya, and have formed good cooperation already.

Part Six: Our Development Orientation

Practice our mission and conquer more difficult diseases.
① Treating kidney disease is our main task;
② Chinese medicine treatment is the preferred treatment in our lifelong, and we will actively absorb the achievements of modern medicine;
③ We aspire for overcoming chronic intractable kidney diseases, and strive to reduce the space and proportion of renal failure and end stage of kidney disease;
④ We are determined to conquer the hard problem of kidney disease, and build an authoritative hospital of traditional Chinese medicine in the world.

Viber:008615931093124

Email:kdtinchina@yahoo.com

From Dr.Leo

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