Urinary protein 2 + serious

Urinary protein causes tubulointerstitial hypoxia worsening:

protein urine reabsorption requires extra energy to digest large amounts of protein, which can cause hypoxia of tubule cells, resulting in tubular cell damage. More and more evidence shows that the protein can directly regulate the function of tubule cells, change its growth characteristics and the expression of its cytokines and matrix protein phenotypes, and can cause the release of PDGF, FN and MCP-1 on the basolateral side of tubules and induce the fibrosis process.

Although proteinuria is not particularly noticeable, if it is chronic kidney disease, it must be checked whether there is such a symptom or not, and measures should be taken in time for treatment. Chronic kidney disease proteinuria is not only a sign of kidney damage, a large number of proteins in renal tubular excretion also promote renal tubular epithelial cell inflammation and fibrosis, thereby accelerating the development of chronic kidney disease.

The large amount of urinary protein is one of the major risk factors for the progression of chronic kidney disease to end-stage renal failure, and should therefore be an important target for the treatment of chronic kidney disease. Mesangial toxicity of urine protein: In the proteinuria nephropathy model, apolipoprotein B and apolipoprotein A deposits in the glomerulus with low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) can eventually be accumulated. Causes glomerular sclerosis.

For more information, please follow the facebook homepage account: Life for Kidney patients, which allows you to learn more about the various news at home and abroad, but also allows you to learn more about kidney disease. (Dr.Leo)

Email:kdtinchina@yahoo.com

Online Doctor:008615931093124

Like Us:https://www.facebook.com/LifeforKidneypatients/