Problem:
1, polycystic kidney disease is a genetic disease?
2, the current treatment of polycystic kidney disease where?
3, polycystic kidney disease is what the new treatment?
Why polycystic kidney disease with heredity?
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| from google |
At present, it is certain that the abnormal proliferation of glomerulus lining epithelial cells is one of the important features of polycystic kidney. This abnormal proliferation is due to cell development and maturation regulatory mechanisms have led to problems, leading to lining epithelial cells are always in an immature stage, and therefore continue to proliferate.
Coupled with sodium, potassium, hydrogen, chlorine plasma and creatinine, urea and other molecules of the transport channel abnormalities, so that these substances into the capsule wall to form cyst fluid, polycystic kidney disease gradually formed.
It is unclear why the abnormal epithelial cells in the lining proliferate and the pathways for transport are abnormal, but there is ample evidence that they are associated with the short arm of chromosome 4 or 16.
Chromosome abnormalities, generally related to genetic factors.
Treatment of polycystic kidney disease
The current treatment of polycystic kidney disease are mainly focused on the elimination of symptoms, after all, genetic issues involved, the current level of medical care can not get a breakthrough.
In the early stages, polycystic kidney disease and no special symptoms, only occasionally urinary occult blood, it is not easy to be found.
When the cyst increases gradually, not only the feeling of lumbar rise appears, but also the blood pressure is likely to increase. The former is the result of oppression of the surrounding tissues by the kidneys, the latter of which is renal hypertension due to poor blood circulation in the kidney itself. At this point of treatment to maintain and conditioning based, taking into account the blood pressure.
With the cyst continues to increase, the pressure gradually increased, and the risk of rupture of the cyst, so at this time can be reduced to the cyst by decompression surgery. If cysts rupture, but also for emergency anti-inflammatory treatment.
When the development of polycystic kidney disease to the terminal stage of treatment is transferred to conventional renal failure, uremic treatment options, mainly dialysis, with antihypertensive, diuretic, anti-inflammatory treatment.
From the routine treatment of polycystic kidney disease we can find that the treatment of polycystic kidney disease is actually mainly maintenance, which is because of the lack of drugs to effectively shrink the cyst, it can only be passive.
Research Progress of Polycystic Kidney
In fact, there is still some research on how to inhibit the abnormal proliferation of lining epithelial cells.
Such as celecoxib, rosiglitazone, rapamycin, triptolide, etc., have a certain effect.
Currently available methods, mainly Chinese medicine.
Some components of traditional Chinese medicine (such as Tripterygium) inhibit the proliferation of lining cells, can slow the rate of cyst growth. On the other hand, the traditional Chinese medicine "Huoxue Po Yu" treatment can use traditional Chinese medicine to activate the parietal cells, cystic fluid gradually absorbed, thereby reducing the cyst.
Therefore, in the early stages of polycystic kidney disease, traditional Chinese medicine treatment can play a significant role in delaying the progression of the disease. Combined with anti-inflammatory and antihypertensive treatment of Western medicine, although it can not completely solve the problem of gene, it can also achieve satisfactory results The treatment effect.
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