2018年1月25日星期四

Why the misunderstanding of creatinine is the key to uremia

I found that many patients with kidney disease although very aware of elevated creatinine, but do not know exactly how serious.
Today we are going to say, what does serum creatinine mean in the end?

creatinine
Causes of elevated serum creatinine
Creatinine is a small molecule substance that is a product of muscle metabolism. Creatinine produced on a daily basis is also essentially fixed due to the relatively constant amount of muscle in our body.
Creatinine flows through the kidneys as it passes through the kidneys, is filtered by the glomerulus, enters the original urine, but does not reabsorb the tubules, so creatinine excretes with the urine.
There are two main reasons for the rise of serum creatinine:
First, eating too much meat or too much exercise, resulting in glomerular filtration of all creatinine too late, so that part of the creatinine back into the blood, causing serum creatinine increased;
Second, the glomerular damage is more serious, inability to filter through all creatinine, will make part of creatinine back into the blood, causing serum creatinine increased.
We often say that patients with renal serum creatinine increased, referring to the second case.

What does serum creatinine mean?
Some people say that although their serum creatinine beyond the normal, but just beyond a little bit, should be okay?
This is a misunderstanding.
Unlike creatinine and occult blood creatinine, mild renal damage does not cause elevated serum creatinine, and only more than half of nephron damage, serum creatinine began to rise.
Therefore, serum creatinine more than 110μmoI / L, does not mean that you can sit back and relax.

Serum creatinine increased how to do?
Many patients with early stage renal failure are confused: more than 700μmoI / L can choose dialysis, but before that? In particular, serum creatinine 500μmoI / L below the kidney disease patients, do not know how to treat.
Currently there are three main ways to reduce creatinine:
First, drugs, such as carbon tablets (love West), proprietary Chinese medicines (uremic clearance), the general effect, better than nothing;
Second, dialysis, here refers to the colon dialysis, that is, traditional Chinese medicine enema, the main method is to use colon decontamination creatinine, the effect is better than the drug;
Third, Chinese medicine treatment, for Chinese medicine, creatinine is "poison evil", Chinese medicine is the way to clean up the evil of qi and blood to improve the body's own ability to detoxify, especially sweating and urination, known as "ghost gate, clean House ". The effect varies from person to person, mainly to dialectical treatment of Chinese medicine is relatively rare.
In addition, should also be combined with diet and lifestyle adjustments, such as reducing meat intake, reduce physical activity and so on. The idea that some patients with kidney disease try to enhance their physique through exercise is good, but exercise produces a lot of creatinine, which is not worth the money for patients with renal insufficiency.

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